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Alternative name
AUTSX3, DKFZp686A24160, MeCp 2 protein, MECP2, Methyl CpG binding protein 2, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT antibody
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Catalog
A005082
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB,IF
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PurificationImmunogen affinity purified
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Immunogenmethyl CpG binding protein 2 (Rett syndrome)
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A005082(MECP2 antibody) at dilution of 1:50
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Western BlotMDA-MB-453s cells were subjected to SDS PAGE followed by western blot with A005082( MECP2 Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalChromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
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Gene nameMECP2
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Uniprot IDP51608
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Observed M.W.75 kDa
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