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Alternative name
ARC105, CTG7A, PCQAP, TIG1, TNRC7 antibody
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Catalog
A005089
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenmediator complex subunit 15
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A005089(MED15 antibody) at dilution of 1:100
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A005089(MED15 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.
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Gene nameMED15
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Uniprot IDQ96RN5
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Observed M.W.105 kDa
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