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Alternative name
MGMT antibody
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Catalog
A005169
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenO-6-methylguanine-DNA methyltransferase
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IHCImmunohistochemistry of paraffin-embedded human kidney using A005169(MGMT antibody) at dilution of 1:100
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A005169(MGMT antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalInvolved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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Gene nameMGMT
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Uniprot IDP16455
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Observed M.W.22 kDa
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