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Alternative name
MICAL, NICAL antibody
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Catalog
A005177
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IP,FC
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PurificationImmunogen affinity purified
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Immunogenmicrotubule associated monoxygenase, calponin and LIM domain containing 1
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IHCImmunohistochemistry of paraffin-embedded human lung using A005177(MICAL1 antibody) at dilution of 1:100
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A005177(MICAL1 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalMonooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.
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Gene nameMICAL1
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Uniprot IDQ8TDZ2
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Observed M.W.120 kDa
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