-
Alternative name
ABI2 Synonyms Abelson interactor 2, ABI 2, ABI2, ABI2B, Abl binding protein 3, abl interactor 2, AblBP3, AIP 1, Arg binding protein 1, ArgBP1, argBPIA, argBPIB, SSH3BP2 antibody
-
Catalog
A000052
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IF,IHC
-
PurificationImmunogen affinity purified
-
Immunogenabl interactor 2
-
IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A000052( ABI2 Antibody) at dilution of 1:50
-
Western Blotmouse heart tissue were subjected to SDS PAGE followed by western blot with A000052(ABI2 antibody) at dilution of 1:400
-
Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100
-
Product Description specificalMay act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.
-
Gene nameABI2
-
locationCell projection,Cytoplasm,Cytoskeleton
-
Uniprot IDQ9NYB9
-
Calculated M.W.56kDa
-
Observed M.W.60-70 kDa
-