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Alternative name
MLF1, myeloid leukemia factor 1 antibody
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Catalog
A005210
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenmyeloid leukemia factor 1
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A005210(MLF1 antibody) at dilution of 1:100
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Western Blotmouse heart tissue were subjected to SDS PAGE followed by western blot with A005210(MLF1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalInvolved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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Gene nameMLF1
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Uniprot IDP58340
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Observed M.W.31 kDa
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