Product Categories
-
Alternative name
BC028141, FLJ34389, MLKL antibody
-
Catalog
A005217
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB
-
PurificationImmunogen affinity purified
-
Immunogenmixed lineage kinase domain-like
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalPseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
-
Gene nameMLKL
-
Uniprot IDQ8NB16
-
Observed M.W.54 kDa
-