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Alternative name
malonyl CoA decarboxylase, MCD, MLYCD antibody
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Catalog
A005225
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogenmalonyl-CoA decarboxylase
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IHCImmunohistochemistry of paraffin-embedded human kidney using A005225(MLYCD antibody) at dilution of 1:50
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Western Blothuman testis tissue were subjected to SDS PAGE followed by western blot with A005225(MLYCD antibody) at dilution of 1:400
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalCatalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation.
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Gene nameMLYCD
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Uniprot IDO95822
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Observed M.W.50kd,55kd,66kd
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