-
Alternative name
CENTD3 antibody
-
Catalog
A000523
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,IHC,WB
-
PurificationImmunogen affinity purified
-
ImmunogenArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
-
IHCImmunohistochemistry of paraffin-embedded human colon tissue slide using A000523( ARAP3 Antibody) at dilution of 1:50
-
Western BlotTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with A000523( ARAP3 Antibody) at dilution of 1:700
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalPhosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
-
Gene nameARAP3
-
Uniprot IDQ8WWN8
-
Observed M.W.45 kDa
-