-
Alternative name
NUDE antibody
-
Catalog
A005600
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF,IP
-
PurificationImmunogen affinity purified
-
ImmunogennudE nuclear distribution gene E homolog 1 (A. nidulans)
-
IHCImmunohistochemistry of paraffin-embedded human breast cancer using A005600(NDE1 antibody) at dilution of 1:100
-
Western BlotA2780 cells were subjected to SDS PAGE followed by western blot with A005600(NDE1 antibody) at dilution of 1:1500
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalRequired for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post- mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.
-
Gene nameNDE1
-
Uniprot IDQ9NXR1
-
Observed M.W.40kd
-