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Alternative name
COOL1, KIAA0142, P85SPR, PAK3BP, PIXB antibody
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Catalog
A000564
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IP,WB
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PurificationImmunogen affinity purified
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ImmunogenRho guanine nucleotide exchange factor (GEF) 7
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalActs as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
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Gene nameARHGEF7
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Uniprot IDQ14155
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Observed M.W.70 kDa
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