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Alternative name
NIT1, nitrilase 1, Nitrilase homolog 1 antibody
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Catalog
A005741
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogennitrilase 1
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A005741(NIT1 antibody) at dilution of 1:50
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Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A005741(NIT1 antibody) at dilution of 1:100
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalPlays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity).
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Gene nameNIT1
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Uniprot IDQ86X76
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Observed M.W.36kd
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