-
Alternative name
NALP2, NBS1, PAN1, PYPAF2 antibody
-
Catalog
A005758
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
ImmunogenNLR family, pyrin domain containing 2
-
IHCImmunohistochemistry of paraffin-embedded human placenta using A005758(NLRP2 antibody) at dilution of 1:50
-
Western BlotA549 cells were subjected to SDS PAGE followed by western blot with A005758(NLRP2 antibody) at dilution of 1:500
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalSuppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
-
Gene nameNLRP2
-
Uniprot IDQ9NX02
-
Observed M.W.105-110 kDa
-