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Alternative name
NOD26, NOD5, NOD9 antibody
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Catalog
A005759
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IHC,IP
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PurificationImmunogen affinity purified
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ImmunogenNLR family member X1
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IHCImmunohistochemistry of paraffin-embedded human heart tissue slide using A005759( NLRX1 Antibody) at dilution of 1:200
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Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A005759(NLRX1 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalParticipates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF- Kappa-B and type 1 interferon signaling pathways, but enhances NF- Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
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Gene nameNLRX1
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Uniprot IDQ86UT6
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Observed M.W.100-110 kDa
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