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Alternative name
h Numb, NUMB, numb homolog (Drosophila), Protein numb homolog, Protein S171, S171 antibody
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Catalog
A005914
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF,FC
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PurificationImmunogen affinity purified
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Immunogennumb homolog (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded human brain using A005914(NUMB antibody) at dilution of 1:100
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A005914(NUMB antibody) at dilution of 1:800
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalPlays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
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Gene nameNUMB
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Uniprot IDP49757
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Observed M.W.66-72 kDa
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