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Alternative name
NUP75, PCNT1 antibody
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Catalog
A005929
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogennucleoporin 85kDa
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IHCImmunohistochemistry of paraffin-embedded human stomach using A005929(NUP85 antibody) at dilution of 1:50
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Western Blotmouse lung tissue were subjected to SDS PAGE followed by western blot with A005929(NUP85 antibody) at dilution of 1:400
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalEssential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.
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Gene nameNUP85
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Uniprot IDQ9BW27
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Observed M.W.70-75kd
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