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Alternative name
P70 alpha, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K 1, p70 S6K alpha, p70 S6KA, p70(S6K) alpha, p70S6K, P70S6K1, PS6K, Ribosomal protein S6 kinase I, RPS6KB1, S6K, S6K beta 1, S6K1, STK14A antibody
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Catalog
A006090
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP,FC
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PurificationImmunogen affinity purified
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Immunogenribosomal protein S6 kinase, 70kDa, polypeptide 1
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A006090( p70(S6K) Antibody) at dilution of 1:200
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A006090(p70(S6K) antibody) at dilution of 1:1200
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Recommended dilutionWB:1:500-1:5000;IP:1:500-1:5000;IHC:1:100-1:400;IF:1:10-1:100
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Product Description specificalRPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation.
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Gene nameRPS6KB1
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locationCell junction,Cytoplasm,Membrane,Mitochondrion,Mitochondrion outer membrane,Nucleus,Synapse,Synaptosome
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Uniprot IDP23443
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Calculated M.W.59kDa,observed 70kDa
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Observed M.W.70 kDa
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