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Alternative name
TOPK antibody
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Catalog
A006180
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,FC
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PurificationImmunogen affinity purified
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ImmunogenPDZ binding kinase
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IHCImmunohistochemistry of paraffin-embedded human placenta using A006180(SPK antibody) at dilution of 1:100
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A006180(SPK antibody) at dilution of 1:600
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalPhosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
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Gene namePBK
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Uniprot IDQ96KB5
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Observed M.W.40kd
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