-
Alternative name
FLJ11105, PI 4 Kinase type 2 beta, PI4K2B, PI4KII BETA, PI4KIIB, PIK42B antibody
-
Catalog
A006425
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF
-
PurificationImmunogen affinity purified
-
Immunogenphosphatidylinositol 4-kinase type 2 beta
-
IHCImmunohistochemistry of paraffin-embedded human liver using A006425(PI4K2B antibody) at dilution of 1:100
-
Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A006425(PI4K2B antibody) at dilution of 1:400
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalTogether with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
-
Gene namePI4K2B
-
Uniprot IDQ8TCG2
-
Observed M.W.50-54kd
-