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Alternative name
NR1C1, PPAR antibody
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Catalog
A006663
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC，IP
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PurificationImmunogen affinity purified
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Immunogenperoxisome proliferator-activated receptor alpha
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IHCImmunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using A006663( PPARA Antibody) at dilution of 1:50
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Western BlotU-937 cells were subjected to SDS PAGE followed by western blot with A006663(PPARA antibody) at dilution of 1:100
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalLigand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
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Gene namePPARA
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Uniprot IDQ07869
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Observed M.W.52-55 kDa
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