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Alternative name
PERC, PGC1, PGC1B, PPARGC1 antibody
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Catalog
A006666
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IP,WB
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PurificationImmunogen affinity purified
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Immunogenperoxisome proliferator-activated receptor gamma, coactivator 1 beta
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalPlays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
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Gene namePPARGC1B
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Uniprot IDQ86YN6
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Observed M.W.100-110 kDa
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