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Alternative name
ARD1, NIPP1 antibody
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Catalog
A006709
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenprotein phosphatase 1, regulatory (inhibitor) subunit 8
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IHCImmunohistochemistry of paraffin-embedded human kidney using A006709(PPP1R8 antibody) at dilution of 1:50
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Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A006709(PPP1R8 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalInhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation._x000D_Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing.
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Gene namePPP1R8
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Uniprot IDQ12972
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Observed M.W.47 kDa,28 kDa,19 kDa
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