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Alternative name
prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1 antibody
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Catalog
A006809
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,FC
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PurificationImmunogen affinity purified
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Immunogenprospero homeobox 1
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IHCImmunohistochemistry of paraffin-embedded human lymphoma using A006809(PROX1 antibody) at dilution of 1:50
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Western Blothuman liver tissue were subjected to SDS PAGE followed by western blot with A006809(PROX1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalTranscription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
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Gene namePROX1
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Uniprot IDQ92786
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Observed M.W.90 kDa
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