anti-RAD1 antibody

Contact Us
  • Alternative name

    REC1 antibody

  • Catalog
    A007073
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IP
  • PurificationImmunogen affinity purified
  • ImmunogenRAD1 homolog (S. pombe)
  • IHCImmunohistochemistry of paraffin-embedded human lymphoma using A007073(RAD1 antibody) at dilution of 1:50
  • Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A007073(RAD1 antibody) at dilution of 1:300
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalComponent of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. Isoform 1 possesses 3'->5' double stranded DNA exonuclease activity.
  • Gene nameRAD1
  • Uniprot IDO60671
  • Observed M.W.32 kDa



Inquiry About anti-RAD1 antibody If you hope to order it or contact us directly, please contact us via sales@biobool.com. We will get back to you in 12hrs,Thanks!