-
Alternative name
C11orf13, HRC1 antibody
-
Catalog
A007138
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse ,Rat
-
Applications Tested/SuitableELISA,WB
-
PurificationImmunogen affinity purified
-
ImmunogenRas association (RalGDS/AF-6) domain family (N-terminal) member 7
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalNegatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
-
Gene nameRASSF7
-
Uniprot IDQ02833
-
Observed M.W.36 kDa,40 kDa
-