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Alternative name
G0S8 antibody
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Catalog
A007269
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenregulator of G-protein signaling 2, 24kDa
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A007269(RGS2 antibody) at dilution of 1:50
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Western Blotfetal human brain tissue were subjected to SDS PAGE followed by western blot with A007269( RGS2 Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalRegulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
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Gene nameRGS2
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Uniprot IDP41220
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Observed M.W.30-32 kDa
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