-
Alternative name
RGS7 antibody
-
Catalog
A007273
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogenregulator of G-protein signaling 7
-
IHCImmunohistochemistry of paraffin-embedded human gliomas using A007273(RGS7 antibody) at dilution of 1:50
-
Western BlotSH-SY5Y cells were subjected to SDS PAGE followed by western blot with A007273(RGS7 antibody) at dilution of 1:500
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalRegulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).
-
Gene nameRGS7
-
Uniprot IDP49802
-
Observed M.W.62 kDa
-