-
Alternative name
ACACA Synonyms ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1 antibody
-
Catalog
A000077
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IP,IF
-
PurificationImmunogen affinity purified
-
Immunogenacetyl-Coenzyme A carboxylase alpha
-
IHCImmunohistochemistry of paraffin-embedded human skeletal muscle using A000077(ACACA antibody) at dilution of 1:50
-
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A000077(ACACA antibody) at dilution of 1:500
-
Recommended dilutionWB :1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200;IP:1:200-1:2000
-
Product Description specificalACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
-
Gene nameACACA
-
locationCytoplasm
-
Uniprot IDQ13085
-
Calculated M.W.270kDa
-
Observed M.W.260-270 kDa
-