-
Alternative name
SENP1, Sentrin specific protease 1, SuPr 2 antibody
-
Catalog
A007712
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,IHC,WB
-
PurificationImmunogen affinity purified
-
ImmunogenSUMO1/sentrin specific peptidase 1
-
IHCImmunohistochemistry of paraffin-embedded human ovary tissue slide using A007712( SENP1 Antibody) at dilution of 1:50
-
Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A007712( SENP1 Antibody) at dilution of 1:1000
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalProtease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032).
-
Gene nameSENP1
-
Uniprot IDQ9P0U3
-
Observed M.W.73 kDa
-