-
Alternative name
BOG25, EHB10, TTP antibody
-
Catalog
A007830
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IF,IP
-
PurificationImmunogen affinity purified
-
ImmunogenSH3-domain binding protein 4
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalMay function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin- mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
-
Gene nameSH3BP4
-
Uniprot IDQ9P0V3
-
Observed M.W.120 kDa
-