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Alternative name
BBC6, BCL2L8 antibody
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Catalog
A000784
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenBCL2-associated agonist of cell death
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IHCImmunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using A000784( BAD Antibody) at dilution of 1:200
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Western Blotmouse heart tissue were subjected to SDS PAGE followed by western blot with A000784(BAD antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalPromotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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Gene nameBAD
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Uniprot IDQ92934
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Observed M.W.15-18 kDa; 25 kDa
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