-
Alternative name
SIKE antibody
-
Catalog
A007867
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogensuppressor of IKK epsilon
-
IHCImmunohistochemistry of paraffin-embedded human liver using A007867(SIKE1 antibody) at dilution of 1:50
-
Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A007867(SIKE1 antibody) at dilution of 1:500
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalPhysiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
-
Gene nameRP5-1000E10.4
-
Uniprot IDQ9BRV8
-
Observed M.W.26 kDa
-