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Alternative name
dJ1104E15.3, FLJ20232, HSU79252, MID51, MIEF1, SMCR7L antibody
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Catalog
A008023
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenSmith-Magenis syndrome chromosome region, candidate 7-like
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Western BlotHT-1080 cells were subjected to SDS PAGE followed by western blot with A008023(SMCR7L antibody) at dilution of 1:400
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Recommended dilutionWB : 1:500-1:5000
IP : 1:500-1:5000
IF : 1:10-1:100
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Product Description specificalHuman SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa (also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.
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Uniprot IDQ9NQG6
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Calculated M.W.51 kDa
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