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Alternative name
HSAN, HSAN1, HSN1, LBC1, LCB 1, LCB1, Serine palmitoyltransferase 1, SPT 1, SPT1, SPTI, SPTLC1 antibody
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Catalog
A008206
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenserine palmitoyltransferase, long chain base subunit 1
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A008206(SPTLC1 antibody) at dilution of 1:100
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A008206(SPTLC1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:1000-1:10000
IP : 1:200-1:2000
IHC : 1:20-1:200
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Product Description specificalSerine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1- SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.
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Gene nameSPTLC1
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Uniprot IDO15269
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Calculated M.W.55kd
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Observed M.W.55kd
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