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Alternative name
ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase antibody
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Catalog
A008209
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP,IF
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PurificationImmunogen affinity purified
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Immunogensqualene epoxidase
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A008209( SQLE Antibody) at dilution of 1:50
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Western BlotA549 cells were subjected to SDS PAGE followed by western blot with A008209(SQLE antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200
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Product Description specificalSQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
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Gene nameSQLE
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Uniprot IDQ14534
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Calculated M.W.64 kDa
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Observed M.W.64 kDa
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