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Alternative name
pp7684, SRA, SRA1, SRAP, STRAA1 antibody
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Catalog
A008213
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogensteroid receptor RNA activator 1
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A008213( SRA1 Antibody) at dilution of 1:50
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Western BlotMCF-7 cells were subjected to SDS PAGE followed by western blot with A008213( SRA1 Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IF:1:50-1:500
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Product Description specificalFunctional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
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Gene nameSRA1
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locationCytoplasm,Nucleus
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Uniprot IDQ9HD15
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Calculated M.W.27kDa
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Observed M.W.30 kDa, 33 kDa
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