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Alternative name
TDF antibody
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Catalog
A008244
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogensex determining region Y
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IHCImmunohistochemistry of paraffin-embedded human kidney using A008244(SRY antibody) at dilution of 1:100
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Western Blothuman testis tissue were subjected to SDS PAGE followed by western blot with A008244(SRY antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalTranscriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
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Gene nameSRY
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Uniprot IDQ05066
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Observed M.W.30kd
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