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Alternative name
CHET9, JJAZ1, KIAA0160 antibody
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Catalog
A008406
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogensuppressor of zeste 12 homolog (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded human breast cancer slide using A008406( SUZ12 Antibody) at dilution of 1:50
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A008406(SUZ12 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalPolycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
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Gene nameSUZ12
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Uniprot IDQ15022
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Observed M.W.80-90 kDa
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