-
Alternative name
KIAA1938 antibody
-
Catalog
A008437
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IF
-
PurificationImmunogen affinity purified
-
Immunogensynaptic Ras GTPase activating protein 1 homolog (rat)
-
Recommended dilutionWB : 1:1000-1:10000
-
Product Description specificalMajor constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR- mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).
-
Gene nameSYNGAP1
-
Uniprot IDQ96PV0
-
Observed M.W.148 kDa
-