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Alternative name
DPK, JIK, KDS, MAP3K18 antibody
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Catalog
A008498
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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ImmunogenTAO kinase 3
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IHCImmunohistochemistry of paraffin-embedded human liver tissue slide using A008498( TAOK3 Antibody) at dilution of 1:200
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Western Blothuman liver tissue were subjected to SDS PAGE followed by western blot with A008498(TAOK3 antibody) at dilution of 1:800
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalSerine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
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Gene nameTAOK3
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Uniprot IDQ9H2K8
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Observed M.W.100-105 kDa
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