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Alternative name
NIF3L1BP1 antibody
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Catalog
A008670
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenTHO complex 7 homolog (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded human kidney using A008670(THOC7 antibody) at dilution of 1:100
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Western Blotmouse testis tissue were subjected to SDS PAGE followed by western blot with A008670(THOC7 antibody) at dilution of 1:800
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalRequired for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. _x000D_The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
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Gene nameTHOC7
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Uniprot IDQ6I9Y2
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Observed M.W.24 kDa
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