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Alternative name
ACO1, Aconitase, Aconitase 1, aconitase 1, soluble, ACONS, Citrate hydro lyase, Ferritin repressor protein, IRE BP 1, IREB1, IREBP, IREBP1, Iron regulatory protein 1, IRP1 antibody
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Catalog
A000087
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenaconitase 1, soluble
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Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A000087(ACO1 antibody) at dilution of 1:300
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Recommended dilutionWB :1:200-1:2000
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Product Description specificalACO1 also known as Cytoplasmic aconitate hydratase is a iron sensor. It binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. It functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. It binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low.
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Gene nameACO1
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locationCytoplasm
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Uniprot IDP21399
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Calculated M.W.98kDa
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Observed M.W.98kd
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