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Alternative name
15E1.1, HSPC132, P53CSV, Protein 15E1.1, TRIAP1, WF 1 antibody
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Catalog
A008964
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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ImmunogenTP53 regulated inhibitor of apoptosis 1
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Western BlotTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 15351-1-AP( TRIAP1 Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000
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Product Description specificalInvolved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).
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Gene nameTRIAP1
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Uniprot IDO43715
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Calculated M.W.9kDa,observed 20kDa
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