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Alternative name
RING finger protein 89, RNF89, TRIM6, tripartite motif containing 6 antibody
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Catalog
A008991
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB
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PurificationImmunogen affinity purified
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Immunogentripartite motif-containing 6
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A008991(TRIM6 antibody) at dilution of 1:50
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Western BlotCOLO 320 cells were subjected to SDS PAGE followed by western blot with A008991(TRIM6 Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200
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Product Description specificalE3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response (PubMed:24882218).
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Gene nameTRIM6
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locationCytoplasm
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Uniprot IDQ9C030
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Calculated M.W.56kDa
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Observed M.W.56 kDa
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