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Alternative name
ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB antibody
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Catalog
A009030
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IF,WB,IP
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PurificationImmunogen affinity purified
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Immunogentransient receptor potential cation channel, subfamily V, member 6
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Western Blothuman placenta tissue were subjected to SDS PAGE followed by western blot with A009030( TRPV6 Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IP:1:200-1:1000;IF:1:10-1:100
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Product Description specificalCalcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)- calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
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Gene nameTRPV6
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locationCell membrane
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Uniprot IDQ9H1D0
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Calculated M.W.82kDa,Observed 70kDa
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Observed M.W.83 kDa, 70 kDa
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