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Alternative name
ADF, ATL derived factor, DKFZp686B1993, SASP, Thioredoxin, TRDX, TRX, TRX1, TXN antibody
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Catalog
A009033
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,FC
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PurificationImmunogen affinity purified
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Immunogenthioredoxin
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IHCImmunohistochemistry of paraffin-embedded human liver tissue slide using A009033( TXN Antibody) at dilution of 1:200
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A009033( TXN Antibody) at dilution of 1:2000
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Recommended dilutionWB:1:1000-1:10000;IP:1:200-1:1000;IHC:1:100-1:400;IF:1:20-1:200
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Product Description specificalTXN, TRDX, TRX, TRX1, ADF and SASP, belongs to the thioredoxin family. It participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
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locationCytoplasm,Nucleus,Secreted
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Uniprot IDP10599
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Calculated M.W.12kDa
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