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Alternative name
MT TRX, MTRX, Thioredoxin 2, Thioredoxin, mitochondrial, TRX2, TXN2 antibody
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Catalog
A009034
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenthioredoxin 2
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A009034(TRX2,TXN2 antibody) at dilution of 1:100
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Western BlotRaji cells were subjected to SDS PAGE followed by western blot with A009034(TRX2,TXN2 antibody) at dilution of 1:500
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200
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Product Description specificalTXN2(Thioredoxin-2) is also named as TRX2,MTRX,Mt-TRX and regulates the mitochondrial redox state and plays an important role in cell proliferation.It has been shown that cells conditionally deficient in Trx2 undergo apoptosis in the absence of exogenous stress, accompanied by an accumulation of intracellular ROS, the activation of caspase 9 and caspase 3, and the release of cytochrome c into the cytosol.In the retina, the expression profile and the role of Trx2 have not yet been defined(PMID:18441302).
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Gene nameTXN2
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locationMitochondrion
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Uniprot IDQ99757
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Calculated M.W.18kDa,Observed 12kDa
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Observed M.W.12 kDa
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