-
Alternative name
KIAA0847, SCA11, tau tubulin kinase 2, TTBK, TTBK2 antibody
-
Catalog
A009076
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogentau tubulin kinase 2
-
IHCImmunohistochemistry of paraffin-embedded human brain using A009076(TTBK2 antibody) at dilution of 1:100
-
Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A009076(TTBK2 antibody) at dilution of 1:400
-
Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IF:1:20-1:200
-
Product Description specificalSerine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.
-
Gene nameTTBK2
-
locationNucleus,ytoplasm
-
Uniprot IDQ6IQ55
-
Calculated M.W.137kDa,Observed 150kDa
-
Observed M.W.137-150 kDa
-