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Alternative name
PCGF4, RNF51 antibody
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Catalog
A000913
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenBMI1 polycomb ring finger oncogene
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IHCImmunohistochemistry of paraffin-embedded human liver cancer using A000913(BMI1 antibody) at dilution of 1:50
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Western BlotU-937 cells were subjected to SDS PAGE followed by western blot with A000913(BMI1 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalComponent of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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Gene nameBMI1
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Uniprot IDP35226
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Observed M.W.43-45 kDa
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