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Alternative name
GRIM 12, GRIM12, KDRF, thioredoxin reductase 1, Thioredoxin reductase TR1, TR, TR1, TRXR1, TXNR, TXNRD1 antibody
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Catalog
A009133
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,FC,IP
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PurificationImmunogen affinity purified
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Immunogenthioredoxin reductase 1
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A009133(TXNRD1 antibody) at dilution of 1:100
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A009133(TXNRD1 antibody) at dilution of 1:500
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100;IP:1:200-1:2000
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Product Description specificalIsoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
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Gene nameTXNRD1
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locationCytoplasm,Nucleus
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Uniprot IDQ16881
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Calculated M.W.55kDa
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Observed M.W.55 kDa
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